|
AMICUS THERAPEUTICS, INC.
|
25,122,048
|
$354,723,000
|
5.18%
|
-60,316
|
-$25,027,000
|
|
IOVANCE BIOTHERAPEUTICS, INC.
|
10,085,632
|
$332,019,000
|
4.85%
|
-1,723,862
|
+$7,849,000
|
|
Global Blood Therapeutics, Inc.
|
5,800,996
|
$319,867,000
|
4.67%
|
-41,104
|
-$48,944,000
|
|
CYTOKINETICS INC
NOTE 4.000%11/1
|
9,770,000
|
$218,301,000
|
3.19%
|
-230,000
|
-$19,959,000
|
|
SpringWorks Therapeutics, Inc.
|
3,481,148
|
$165,946,000
|
2.42%
|
-33,210
|
+$18,343,000
|
|
NEUROCRINE BIOSCIENCES INC
|
1,548,715
|
$148,924,000
|
2.17%
|
-592,695
|
-$112,328,000
|
|
NEVRO CORP
|
826,164
|
$115,085,000
|
1.68%
|
-73,808
|
+$7,565,000
|
|
Kodiak Sciences Inc.
|
1,043,021
|
$61,757,000
|
0.90%
|
-2,470,551
|
-$128,397,000
|
|
Blueprint Medicines Corp
|
664,574
|
$61,606,000
|
0.90%
|
-24,050
|
+$7,893,000
|
|
Provention Bio, Inc.
|
4,265,711
|
$54,729,000
|
0.80%
|
-260,000
|
-$9,129,000
|
|
ARENA PHARMACEUTICALS INC
|
625,129
|
$46,753,000
|
0.68%
|
-470,000
|
-$22,185,000
|
|
Allogene Therapeutics, Inc.
|
1,143,790
|
$43,132,000
|
0.63%
|
-400,000
|
-$22,973,000
|
|
Morphic Holding, Inc.
|
487,000
|
$13,314,000
|
0.19%
|
-163,000
|
-$4,269,000
|
|
DBV Technologies S.A.
SPONSORED ADR
|
6,806,975
|
$11,776,000
|
0.17%
|
-510,834
|
-$20,349,000
|
|
HOLOGIC INC
|
170,000
|
$11,300,000
|
0.16%
|
-60,000
|
-$1,810,000
|
|
Health Catalyst, Inc.
|
291,084
|
$10,654,000
|
0.16%
|
-44,698
|
+$859,000
|
|
INSULET CORP
|
37,733
|
$8,927,000
|
0.13%
|
-15,000
|
-$1,317,000
|
|
AtriCure, Inc.
|
216,449
|
$8,636,000
|
0.13%
|
-312,327
|
-$15,132,000
|
|
Twist Bioscience Corp
|
112,756
|
$8,566,000
|
0.13%
|
-160,000
|
-$3,790,000
|
|
Revolution Medicines, Inc.
|
224,224
|
$7,803,000
|
0.11%
|
-125,776
|
-$3,247,000
|
|
REGENERON PHARMACEUTICALS, INC.
|
5,000
|
$2,799,000
|
0.04%
|
-10,000
|
-$6,555,000
|
|
Livongo Health, Inc.
|
10,663
|
$1,493,000
|
0.02%
|
-2,957
|
+$469,000
|
|
BIO-RAD LABORATORIES, INC.
CL A
|
489
|
$252,000
|
0.00%
|
-15,000
|
-$6,741,000
|